CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer: Cell
CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38α/MYC/PD-L1 signaling in non-small cell lung cancer | Journal of Hematology & Oncology | Full Text
THZ1 | CDK7 Inhibitor | MedChemExpress
THZ1 Inhibits the CDK7 Kinase Activity, Pol II CTD Phosphorylation, and... | Download Scientific Diagram
ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942 | Oncogene
New Pre-clinical Research Shows Transcription-Targeting Drug Useful in T-cell Lymphoma – New Developments in Lymphoma
THZ1 reveals CDK7-dependent transcriptional addictions in pancreatic cancer | Oncogene
Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation | Cell Death & Disease
Frontiers | CDK7 Inhibitor THZ1 Induces the Cell Apoptosis of B-Cell Acute Lymphocytic Leukemia by Perturbing Cellular Metabolism
Cyclin-dependent kinase 7 inhibitor THZ1 in cancer therapy - ScienceDirect
CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists
Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors - ScienceDirect
TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters - Journal of Biological Chemistry
Inhibition of CDK7 by THZ1 Sensitizes Cancer Cells to PARPi-Induced DNA... | Download Scientific Diagram
CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263 | Cell Death & Disease
CDK7 inhibitors as anticancer drugs | SpringerLink
CDK7 inhibitors as anticancer drugs | SpringerLink
THZ1 | CDK7 Inhibitor | MedChemExpress
ThZ1 causes cell cycle arrest, shuts off proliferation, and induces... | Download Scientific Diagram
Frontiers | CDK7 Inhibitor THZ1 Induces the Cell Apoptosis of B-Cell Acute Lymphocytic Leukemia by Perturbing Cellular Metabolism
CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263 | Cell Death & Disease
CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38α/MYC/PD-L1 signaling in non-small cell lung cancer | Journal of Hematology & Oncology | Full Text
Inhibition of CDK7 by THZ1 Represses the Expression of Genes in the DDR... | Download Scientific Diagram
CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors | Nature Communications
ThZ1 inhibits growth of gBM in vitro and in vivo. Notes: (A) Top ranked... | Download Scientific Diagram
